Shanghai Weiwei Bio-Research on the Characteristics of Medium Proteins - Huaqiang Electronic Network

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Characteristics of medium protein:

one,

For humans

:

Proteomics research eventually

Are all

To serve human health

for purpose

Mainly refers to the promotion of the development of molecular medicine. For example, looking for a target molecule for a drug. Many drugs are proteins themselves, and the target molecules of many drugs are also proteins. Drugs can also interfere with protein-protein interactions.

two,

Post-translational modification

:

Many proteins produced by mRNA expression undergo post-translational modification

,

Such as phosphorylation, glycosylation, zymogen activation and the like. Post-translational modification is an important means of protein regulation, so the study of post-translational modification of proteins plays an important role in elucidating the function of proteins.

three,

Its protein identification

:

Proteins can be identified by one-dimensional electrophoresis and two-dimensional electrophoresis combined with Western techniques, using protein chips, antibody chips and immunoprecipitation techniques.

four,

Medium protein

Got

Function determination

:

For example, analysis of enzyme activity and determination of enzyme substrates, bioanalytical/ligand-receptor binding assays of cytokines. The gene expression product-protein function can be analyzed using gene knockout and antisense techniques. In addition, the localization of the protein after expression of the protein also contributes to the understanding of protein function to some extent. Clontech's fluorescent protein expression system is a good tool for studying the localization of proteins in cells.

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